PF-06679142
目录号: A22484
AMPK activator
PF-06679142 是一种强效的 AMPK 激活剂。在临床前物种中,PF-06679142 在大鼠肾脏中展示了强大的 AMPK 激活效果,同时具有理想的口服吸收、低血浆清除率和可忽略的肾脏清除率。
Discription | PF-06679142 is a potent AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption, low plasma clearance, and negligible renal clearance in preclinical species. |
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目录号 | A22484 |
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分子式 | C20H17F2NO3 |
分子量 | 357.3568 |
CAS号 | 1467059-66-0 |
SMILES | O=C(C1=CNC2=C1C(F)=C(C3=CC=C([C@@H]4CCCCO4)C=C3)C(F)=C2)O |
其他名称 | PF-06679142, PF06679142, PF 06679142, PF-6679142, PF6679142, PF 6679142, |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2