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RG3039 (PF-06687859)是口服可生物利用的,脑渗透性小分子,已被证明是mRNA脱壳酶DcpS的抑制剂。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.13 mL | 115.65 mL | 231.29 mL |
0.5 mM | 4.63 mL | 23.13 mL | 46.26 mL |
1 mM | 2.31 mL | 11.56 mL | 23.13 mL |
5 mM | 0.46 mL | 2.31 mL | 4.63 mL |
*The above data is based on the productmolecular weight 432.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13835 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 432.35 |
Formula | C21H23Cl2N5O |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1005504-62-0 |
Synonyms | RG-3039, RG3039 |
SMILES | NC1=NC(N)=C2C(OCC3CCN(CC4=C(Cl)C=CC=C4Cl)CC3)=CC=CC2=N1.[H]Cl.[H]Cl |
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