PF-06726304
目录号: A16937
EZH2 抑制剂
PF-06726304 是一种强效的、与SAM(S-腺苷甲硫氨酸)竞争的 EZH2 (Enhancer of Zeste Homolog 2) 赖氨酸甲基转移酶抑制剂。
Discription | PF-06726304 is a potent and SAM-competitive EZH2 (Enhancer of Zeste Homolog 2) lysine methyltransferase inhibitor. | |||||
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Targets |
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Cell Research |
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目录号 | A16937 |
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分子式 | C22H21Cl2N3O3 |
分子量 | 446.32 |
CAS号 | 1616287-82-1 |
SMILES | O=C1N(CC2=C(C)C=C(C)NC2=O)CCC3=C1C(Cl)=C(C4=C(C)ON=C4C)C=C3Cl |
其他名称 | PF 06726304, PF06726304 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 9 mg/mL (20.16 mM) | |
Water | Insoluble | ||
Ethanol | 20 mg/mL (44.81 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.41 mL | 112.03 mL | 224.05 mL |
0.5 mM | 4.48 mL | 22.41 mL | 44.81 mL |
1 mM | 2.24 mL | 11.2 mL | 22.41 mL |
5 mM | 0.45 mL | 2.24 mL | 4.48 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2