PF-06747711
目录号: A19605
RORγt inverse agonist
PF-06747711 是一种强效、选择性且口服活性的视黄酸受体相关孤儿C2(RORC2,也称为RORγt)反向激动剂,具有 4.1 nM 的 IC50 值。具有抗皮肤炎症活性。
Discription | PF-06747711 is a potent, selective, and orally active retinoic acid receptor-related orphan C2 (RORC2, also known as RORγt) inverse agonist, with an IC50 of 4.1 nM. Anti-skin inflammatory activity. |
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目录号 | A19605 |
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分子式 | C26H26F3N5O2 |
分子量 | 497.51 |
CAS号 | 1892576-58-7 |
SMILES | O=C(NC1=CN=C(N(C)C=C2C3CCN(C(C(C)C)=O)CC3)C2=C1C(F)(F)F)C4=CC=CC(C#N)=C4 |
其他名称 | PF06747711, PF 06747711 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2