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PF-06747711

PF-06747711

Name: PF-06747711
SKU: A19605

目录号: A19605

RORγt inverse agonist

PF-06747711 Chemical Structure

CAS NO. 1892576-58-7

PF-06747711 is a potent, selective, and orally active retinoic acid receptor-related orphan C2 (RORC2, also known as RORγt) inverse agonist, with an IC50 of 4.1 nM. Anti-skin inflammatory activity.

库存：现货

规格	价格	数量
5 mg	￥ 1,008.00
10 mg	￥ 1,736.00
50 mg	￥ 5,152.00
100 mg	￥ 10,304.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

PF-06747711 is a potent, selective, and orally active retinoic acid receptor-related orphan C2 (RORC2, also known as RORγt) inverse agonist, with an IC50 of 4.1 nM. Anti-skin inflammatory activity.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.1 mL	100.5 mL	201 mL
0.5 mM	4.02 mL	20.1 mL	40.2 mL
1 mM	2.01 mL	10.05 mL	20.1 mL
5 mM	0.4 mL	2.01 mL	4.02 mL

*The above data is based on the productmolecular weight 497.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19605
M. Wt	497.51
Formula	C26H26F3N5O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1892576-58-7
Synonyms	PF06747711, PF 06747711
SMILES	O=C(NC1=CN=C(N(C)C=C2C3CCN(C(C(C)C)=O)CC3)C2=C1C(F)(F)F)C4=CC=CC(C#N)=C4