PF-06855800
目录号: A16860
PRMT5 抑制剂
PF-06855800(PF06855800)是一种强效、选择性、与SAM竞争的、能穿透血脑屏障(BBB)的、口服活性的蛋白精氨酸甲基转移酶PRMT5抑制剂,其Ki值为0.02 nM。
Discription | PF-06855800 (PF06855800) is a potent, selective, SAM competitive, BBB-penetrant, orally active inhibitor of protein arginine methyltransferase PRMT5 with Ki of 0.02 nM. |
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目录号 | A16860 |
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分子式 | C17H16ClFN4O4 |
分子量 | 394.8 |
CAS号 | 1989620-04-3 |
SMILES | C1=CC(=C(C=C1[C@H]([C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)O)O)O)F)Cl |
其他名称 | PF06855800, PF 06855800, Prmt5-IN-2 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2