目录号: A11183
FAAH Inhibitor
PF-3845 是一种强效、选择性且不可逆的 FAAH 抑制剂(Ki = 0.23 μM)。它通过依赖 大麻素受体 的机制减轻炎症性疼痛。
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生物活性
Discription | PF-3845 is a potent, selective, and irreversible inhibitor of FAAH (Ki = 0.23 μM). It reduces inflammatory pain via a cannabinoid receptor-dependent mechanism. |
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产品信息
目录号 | A11183 |
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分子式 | C24H23F3N4O2 |
分子量 | 456.46 |
CAS号 | 1196109-52-0 |
SMILES | C1CN(CCC1CC2=CC(=CC=C2)OC3=NC=C(C=C3)C(F)(F)F)C(=O)NC4=CN=CC=C4 |
其他名称 | PF3845 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
In vitro (25°C) | DMSO | 87 mg/mL (190.6 mM) | |
Water | Insoluble | ||
Ethanol | 87 mg/mL (190.6 mM) | ||
In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 14 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Preparing Stock Solutions
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.91 mL | 109.54 mL | 219.08 mL |
0.5 mM | 4.38 mL | 21.91 mL | 43.82 mL |
1 mM | 2.19 mL | 10.95 mL | 21.91 mL |
5 mM | 0.44 mL | 2.19 mL | 4.38 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 PF-3845 | PF-3845 供应商 | PF-3845 花费 | PF-3845 生产商 | 订购 PF-3845 | PF-3845 代理商
| 购买 1196109-52-0 | 1196109-52-0 供应商 | 1196109-52-0 花费 | 1196109-52-0 生产商 | 订购 1196109-52-0 | 1196109-52-0 代理商