PF-4

Name: PF-4
SKU: A13451
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A13451

BRPF1 bromodomain inhibitor

PFI-4 是一种强效且选择性的、能够渗透细胞的 BRPF1 溴结构域抑制剂（IC50 = 80 nM）。相较于包括 BRPF2（BRD1）、BRPF3 和 BRD4 在内的其他溴结构域，展现出超过100倍的选择性。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥385.00	现货
25mg	¥805.00	现货
50mg	¥1,330.00	现货
100mg	¥2,240.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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Data Sheet

SDS

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生物活性

Discription

PFI-4 is a potent and selective and cell permeable BRPF1 bromodomain inhibitor (IC50 = 80 nM). Exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4.

Targets

Target	Value

产品信息

目录号	A13451
分子式	C21H24N4O3
分子量	380.44
CAS号	900305-37-5
SMILES	[H]N(C(C1=CC=CC=C1OC)=O)C2=C(N3CCCC3)C=C(N(C)C(N4C)=O)C4=C2
其他名称	PF4, PF 4
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 17 mg/mL (44.68 mM)
	Water	Insoluble
	Ethanol	Warmed: 5 mg/mL (13.14 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.29 mL	131.43 mL	262.85 mL
0.5 mM	5.26 mL	26.29 mL	52.57 mL
1 mM	2.63 mL	13.14 mL	26.29 mL
5 mM	0.53 mL	2.63 mL	5.26 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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