PF-4136309

Name: PF-4136309
SKU: A15127
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A15127

CCR2 拮抗剂

PF-4136309 是一种强效、选择性且口服生物利用度高的 CCR2 拮抗剂，其对人类、小鼠和大鼠 CCR2 的 IC50 分别为 5.2 nM、17 nM 和 13 nM。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥420.00	现货
10mg	¥735.00	现货
25mg	¥1,330.00	现货
50mg	¥2,240.00	现货
100mg	¥3,360.00	现货
*10mM 1mL in DMSO**	¥560.00	现货
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Data Sheet

SDS

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生物活性

Discription

PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.

Targets

Target	Value

产品信息

目录号	A15127
分子式	C29H31F3N6O3
分子量	568.59
CAS号	1341224-83-6
SMILES	O[C@]1(CC[C@](CC1)([H])N[C@@H]2CN(CC2)C(CNC(C3=CC=CC(C(F)(F)F)=C3)=O)=O)C4=NC=C(C=C4)C5=NC=CC=N5
其他名称	INCB8761
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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