PF-4191834

Name: PF-4191834
SKU: A18777
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A18777

5-LOX inhibitor

PF-4191834 是一种新型、高效且选择性的非氧化型 5-脂氧合酶 抑制剂，对炎症和疼痛具有显著效果，其 IC50 值为 229 nM。该化合物对 5-LOX 的选择性约为 12-LOX 和 15-LOX 的 300 倍，对环氧合酶酶无活性。

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Grouped product items
规格	价格	库存
1mg	¥140.00	现货
5mg	¥280.00	现货
10mg	¥490.00	现货
25mg	¥1,050.00	现货
50mg	¥1,855.00	现货
100mg	¥2,730.00	现货
500mg	¥5,950.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

PF-4191834 is a novel, potent and selective non-redox 5-lipoxygenase inhibitor effective in inflammation and pain with an IC50=229 nM. displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX, shows no activity toward the cyclooxygenase enzymes.

Targets

Target	Value

产品信息

目录号	A18777
分子式	C22H23N3O2S
分子量	393.51
CAS号	1029317-21-2
SMILES	O=C(C1(C2=CC=CC(SC3=CC=C(C4=CC=NN4C)C=C3)=C2)CCOCC1)N
其他名称	PF-04191834; PF04191834; PF 04191834; PF-4191834; PF4191834; PF 4191834.
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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