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PF-4618433与原型BIRB796相比，PF-4618433显示出PYK2效价提高、p38活性降低和总体选择性优越。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.45 mL | 112.23 mL | 224.46 mL |
| 0.5 mM | 4.49 mL | 22.45 mL | 44.89 mL |
| 1 mM | 2.24 mL | 11.22 mL | 22.45 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.49 mL |
*The above data is based on the productmolecular weight 445.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13461 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 445.52 |
| Formula | C24H27N7O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1166393-85-6 |
| Synonyms | PF 4618433, PF4618433 |
| SMILES | Cc1ccc(cc1)n2c(cc(n2)C(C)(C)C)NC(=O)Nc3cc(n[nH]3)COc4cccnc4 |
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