PF-4800567

Name: PF-4800567
SKU: A21381
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A21381

Casein kinase 1ε 抑制剂

PF-4800567 是一种强效且选择性的酪蛋白激酶1ε (CK1ε) 抑制剂，其半抑制浓度（IC50）为32 nM，对酪蛋白激酶1δ (CK1δ) 的选择性超过20倍（IC50为711 nM）。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥350.00	现货
25mg	¥770.00	现货
50mg	¥1,400.00	现货
100mg	¥2,030.00	现货
200mg	¥2,975.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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Data Sheet

SDS

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生物活性

Discription

PF-4800567 is a potent and selective inhibitor of casein kinase 1ε (CK1ε), with an IC50 of 32 nM, which is greater than 20-fold selectivity over CK1δ (IC50, 711 nM).

Targets

Target	Value

产品信息

目录号	A21381
分子式	C17H18ClN5O2
分子量	359.81
CAS号	1188296-52-7
SMILES	NC1=C2C(N(C3CCOCC3)N=C2COC4=CC=CC(Cl)=C4)=NC=N1
其他名称	PF 4800567, PF4800567
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	70 mg/mL (194.54 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.79 mL	138.96 mL	277.92 mL
0.5 mM	5.56 mL	27.79 mL	55.58 mL
1 mM	2.78 mL	13.9 mL	27.79 mL
5 mM	0.56 mL	2.78 mL	5.56 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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