PF-543 Citrate

Name: PF-543 Citrate
SKU: A15210
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A15210

SphK1 Inhibitor

PF-543 Citrate 是一种新型的细胞渗透性抑制剂，针对 SphK1 具有 3.6 nM 的 K(i) 值，PF-543 是与鞘氨醇竞争的，并且对 SphK1 相比 SphK2 异构体具有超过 100 倍的选择性。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥490.00	现货
10mg	¥840.00	现货
50mg	¥2,590.00	现货
100mg	¥3,990.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription	PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-543 is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.

产品信息

目录号	A15210
分子式	C33H39NO11S
分子量	657.73
CAS号	1415562-83-2
SMILES	CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCCC3CO)CS(=O)(=O)C4=CC=CC=C4.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
其他名称	PF543 Citrate, PF 543 Citrate
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	85 mg/mL (169.3 mM)
	Water	Insoluble
	Ethanol	85 mg/mL (169.3 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.2 mL	76.02 mL	152.04 mL
0.5 mM	3.04 mL	15.2 mL	30.41 mL
1 mM	1.52 mL	7.6 mL	15.2 mL
5 mM	0.3 mL	1.52 mL	3.04 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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