产品详情
PF-543 Citrate是一种新型的SphK1细胞渗透抑制剂,K(i)为3.6 nM,PF-543具有鞘氨醇竞争性,对SphK1的选择性是SphK2同种型的100倍以上。
In vitro | DMSO | 85 mg/mL (169.3 mM) | |
Water | Insoluble | ||
Ethanol | 85 mg/mL (169.3 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 15.2 mL | 76.02 mL | 152.04 mL |
0.5 mM | 3.04 mL | 15.2 mL | 30.41 mL |
1 mM | 1.52 mL | 7.6 mL | 15.2 mL |
5 mM | 0.3 mL | 1.52 mL | 3.04 mL |
*The above data is based on the productmolecular weight 657.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A15210 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 657.73 |
Formula | C33H39NO11S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1415562-83-2 |
Synonyms | PF543 Citrate, PF 543 Citrate |
SMILES | CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCCC3CO)CS(=O)(=O)C4=CC=CC=C4.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
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