PF-562271

Name: PF-562271
SKU: A11192
Price: 315 CNY
Rating: 5 (1 reviews)

目录号: A11192

FAK 抑制剂

1 篇发表文献

PF-562271 是一种口服生物利用度高的小分子，具有潜在的抗肿瘤和抗血管生成活性，是一种 ATP竞争性粘着斑激酶（FAK）抑制剂。

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Grouped product items
规格	价格	库存
1mg	¥315.00	现货
5mg	¥805.00	现货
10mg	¥1,085.00	现货
25mg	¥1,855.00	现货
50mg	¥2,730.00	现货
100mg	¥4,130.00	现货
500mg	¥8,715.00	现货
*10mM 1mL in DMSO**	¥945.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用PF-562271发表的1篇文献

Jiping Yue, .et al. , Nat Commun, 2016, 7: 11692 PMID: 27216888

生物活性

Discription

PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11192
分子式	C21H20F3N7O3S
分子量	507.49
CAS号	717907-75-0
SMILES	CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C
其他名称	PF562271
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 91 mg/mL (179.31 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+40% PEG 300+5% Tween 80+50% ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.7 mL	98.52 mL	197.05 mL
0.5 mM	3.94 mL	19.7 mL	39.41 mL
1 mM	1.97 mL	9.85 mL	19.7 mL
5 mM	0.39 mL	1.97 mL	3.94 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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