PF 573228

Name: PF 573228
SKU: A11235
Price: 280 CNY
Rating: 5 (3 reviews)

目录号: A11235

FAK 抑制剂

3 篇发表文献

PF 573228 是一种强效且选择性的焦点粘附激酶 (FAK) 抑制剂（IC50 = 4 nM）。

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Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥455.00	现货
25mg	¥910.00	现货
50mg	¥1,540.00	现货
100mg	¥2,520.00	现货
500mg	¥4,970.00	现货
*10mM 1mL in DMSO**	¥686.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用PF 573228发表的3篇文献

Dagyeong Lee, .et al. , J Transl Med, 2024, Feb 14;22(1):154 PMID: 38355577

Izumi D, .et al. , Int J Cancer, 2016, Mar 1;138(5):1207-19 PMID: 26414794

Aya Yokota-Nakatsuma, .et al. , Sci Rep, 2016, 6: 37914 PMID: 27897208

生物活性

Discription

PF 573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11235
分子式	C22H20F3N5O3S
分子量	491.5
CAS号	869288-64-2
SMILES	CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4
其他名称	PF-573228, PF573228
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	24 mg/mL (48.83 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+2% Tween 80+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.35 mL	101.73 mL	203.46 mL
0.5 mM	4.07 mL	20.35 mL	40.69 mL
1 mM	2.03 mL	10.17 mL	20.35 mL
5 mM	0.41 mL	2.03 mL	4.07 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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