PF-915275
目录号: A21330
11β-HSD1 inhibitor
PF-915275 是一种强效、选择性且可口服的人类11β-羟基类固醇脱氢酶1型(11βHSD1)抑制剂,其Ki值为2.3 nM,EC50值为15 nM(在HEK293细胞中)。
11β-HSD1 inhibitor
Discription | PF-915275 is a potent, selective and orally active human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor with a Ki of 2.3 nM and an EC50 of 15 nM (in HEK293 cells). | |||||
---|---|---|---|---|---|---|
Cell Research |
|
目录号 | A21330 |
---|---|
分子式 | C18H14N4O2S |
分子量 | 350.39 |
CAS号 | 857290-04-1 |
SMILES | N#CC1=CC=C(C2=CC=C(S(NC3=NC(N)=CC=C3)(=O)=O)C=C2)C=C1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2