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PF-CBP1是CREB结合蛋白（CREBBP）溴结构域的高度选择性抑制剂，它抑制CREBBP和p300溴结构域，IC50分别为125和363 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.04 mL | 95.22 mL | 190.45 mL |
| 0.5 mM | 3.81 mL | 19.04 mL | 38.09 mL |
| 1 mM | 1.9 mL | 9.52 mL | 19.04 mL |
| 5 mM | 0.38 mL | 1.9 mL | 3.81 mL |
*The above data is based on the productmolecular weight 525.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15876 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 525.08 |
| Formula | C29H36N4O3.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1962928-21-7 |
| Synonyms | PF-CBP-1, PF-CBP 1, PF-06670910, PF 06670910, PF06670910 |
| SMILES | CCCOC1=CC=C(CCC2=NC3=CC(C4=C(C)ON=C4C)=CC=C3N2CCN5CCOCC5)C=C1 |
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