PHA 408
目录号: A13108
IKK-2 抑制剂
PHA 408 是一种强效、高选择性和 ATP 竞争性的 IKB 激酶-2 (IKK-2) 抑制剂(IC50:40 nM),与 IKK-2 紧密结合,具有相对缓慢的脱离速率;强烈推荐用作研究 IKK-2 如何调控 NF-KB 信号传导的工具。
Discription | PHA 408 is a potent, highly selective and ATP-competitive IKB kinase-2 (IKK-2) inhibitor (IC50: 40 nM), which binds IKK-2 tightly with a relatively slow off rate; highly recommended tool to investigate the mechanisms by which IKK-2 regulates NF-KB signaling. |
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目录号 | A13108 |
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分子式 | C29H27ClFN7O2 |
分子量 | 560.02 |
CAS号 | 503555-55-3 |
SMILES | CN1CCN(CC1)C2=NC=C(C(=C2)C(=O)NC3=CC4=C(CCC5=C4N(N=C5C(=O)N)C6=CC=C(C=C6)F)C=C3)Cl |
其他名称 | PHA-408, PHA408 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2