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PHA 408

目录号: A13108
IKK-2 抑制剂
PHA 408 是一种强效、高选择性和 ATP 竞争性的 IKB 激酶-2 (IKK-2) 抑制剂(IC50:40 nM),与 IKK-2 紧密结合,具有相对缓慢的脱离速率;强烈推荐用作研究 IKK-2 如何调控 NF-KB 信号传导的工具。
Grouped product items
规格 价格 库存 数量
1mg
¥840.00
现货
5mg
¥2,240.00
现货
10mg
¥3,780.00
现货
25mg
¥6,860.00
现货
50mg
¥11,760.00
现货
100mg
¥17,465.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription PHA 408 is a potent, highly selective and ATP-competitive IKB kinase-2 (IKK-2) inhibitor (IC50: 40 nM), which binds IKK-2 tightly with a relatively slow off rate; highly recommended tool to investigate the mechanisms by which IKK-2 regulates NF-KB signaling.
产品信息
目录号 A13108
分子式 C29H27ClFN7O2
分子量 560.02
CAS号 503555-55-3
SMILES CN1CCN(CC1)C2=NC=C(C(=C2)C(=O)NC3=CC4=C(CCC5=C4N(N=C5C(=O)N)C6=CC=C(C=C6)F)C=C3)Cl
其他名称 PHA-408, PHA408
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2

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