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PHA-767491是一种有效的，具有ATP竞争性的双重cdc7/cdk9抑制剂 (IC50值分别为10和34 nM)，可防止DNA复制的启动。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 46.9 mL | 234.48 mL | 468.96 mL |
| 0.5 mM | 9.38 mL | 46.9 mL | 93.79 mL |
| 1 mM | 4.69 mL | 23.45 mL | 46.9 mL |
| 5 mM | 0.94 mL | 4.69 mL | 9.38 mL |
*The above data is based on the productmolecular weight 213.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11164 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 213.24 |
| Formula | C12H11N3O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 845714-00-3 |
| Synonyms | PHA767491 |
| SMILES | C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3 |
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