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PI4KIIIbeta-IN-9是一种有效的PI4KIIIbeta抑制剂（IC50为7 nM），选择性是PI3Kgamma的140倍以上，选择性是PI3Kδ的20倍以上，并且在浓度高达20 uM时，对vps34没有抑制作用。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.51 mL | 102.55 mL | 205.09 mL |
| 0.5 mM | 4.1 mL | 20.51 mL | 41.02 mL |
| 1 mM | 2.05 mL | 10.25 mL | 20.51 mL |
| 5 mM | 0.41 mL | 2.05 mL | 4.1 mL |
*The above data is based on the productmolecular weight 487.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16270 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 487.59 |
| Formula | C23H25N3O5S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1429624-84-9 |
| SMILES | CC1=C(SC(=N1)NC(=O)C2CCCC2)C3=CC(=C(C=C3)OC)S(=O)(=O)NC4=CC=C(C=C4)O |
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