Pifithrin-α hydrobromide

Name: Pifithrin-α hydrobromide
SKU: A12451
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A12451

p53 抑制剂

Pifithrin-α hydrobromide 是一种可逆的 p53 介导的凋亡和 p53 依赖的基因转录抑制剂，如 cyclin G、p21/waf1 和 mdm2 的表达。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥490.00	现货
25mg	¥1,155.00	现货
50mg	¥1,925.00	现货
100mg	¥2,905.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

Pifithrin-α hydrobromide is a reversible inhibitor of p53-mediated apoptosis and p53-dependent gene transcription such as cyclin G, p21/waf1, and mdm2 expression.

Targets

Target	Value

产品信息

目录号	A12451
分子式	C16H18N2OS.HBr
分子量	367.3
CAS号	63208-82-2
SMILES	CC1=CC=C(C=C1)C(=O)CN2C3=C(CCCC3)SC2=N.Br
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	58 mg/mL (157.91 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+ 40% PEG 300+ 5%Tween80+ 50%ddH2O	3.46 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.23 mL	136.13 mL	272.26 mL
0.5 mM	5.45 mL	27.23 mL	54.45 mL
1 mM	2.72 mL	13.61 mL	27.23 mL
5 mM	0.54 mL	2.72 mL	5.45 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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