PIK-III

目录号: A15868

Autophagy 抑制剂

PIK-III

PIK-III Chemical Structure

CAS NO. 1383716-40-2

PIK-III是βVPS34酶活性的选择性抑制剂。

库存: 现货

规格 价格 数量
5 mg
¥ 910.00
10 mg
¥ 1,470.00
25 mg
¥ 3,290.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PIK-III是βVPS34酶活性的选择性抑制剂。
Targets
Target Value
Vps34IC50: 0.018μM
PI3KδIC50: 1.2μM
PI3KγIC50: 3.04μM
PI3KαIC50: 3.96μM
PI4KβIC50: 4.43μM
PI3KβIC50: >9.1μM
mTORIC50: >9.1μM
In vitro DMSO 56 mg/mL (175.34 mM)
Water Insoluble
Ethanol 56 mg/mL (175.34 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.31 mL 156.56 mL 313.13 mL
0.5 mM 6.26 mL 31.31 mL 62.63 mL
1 mM 3.13 mL 15.66 mL 31.31 mL
5 mM 0.63 mL 3.13 mL 6.26 mL

*The above data is based on the productmolecular weight 319.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15868
作用机制 Inhibitor (抑制剂)
M. Wt 319.36
Formula C17H17N7
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1383716-40-2
Synonyms VPS34-IN2
SMILES NC1=NC=C(C2=NC(NC3=CC=NC=C3)=NC=C2)C(CC4CC4)=N1

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