PIM1-IN-1
目录号: A19392
PIM1/3 抑制剂
PIM1-IN-1 是一种高效且高度选择性的 PIM1/3 抑制剂,对 PIM1、PIM2 和 PIM3 的 IC50 分别为 7、5530 和 70 nM,能够抑制 PIM 下游靶点 BAD 的磷酸化,EC50 为 262 nM。
Discription | PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. | |||||
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Cell Research |
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目录号 | A19392 |
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分子式 | C25H30N8O2 |
分子量 | 474.56 |
CAS号 | 1417630-95-5 |
SMILES | COCCN1C2=C(C3=NN=C(C4=NC5=C(NCC6CCNCC6)C=CC=C5C=C4)N3N=C2)OCC1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2