PK11007

目录号: A16833

p53 activator

PK11007

PK11007 Chemical Structure

CAS NO. 38275-34-2

PK11007是一种抗p53药物,可通过两个表面暴露的半胱氨酸的选择性烷基化来稳定野生型和突变型p53,而不会损害其DNA结合活性。它不仅通过重新激活p53发挥抗肿瘤功能,还通过其他细胞机制发挥作用,例如将细胞ROS升高至毒性水平并激活UPR。

库存: 现货

规格 价格 数量
5 mg
¥ 350.00
10 mg
¥ 560.00
50 mg
¥ 1,750.00
100 mg
¥ 2,940.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PK11007是一种抗p53药物,可通过两个表面暴露的半胱氨酸的选择性烷基化来稳定野生型和突变型p53,而不会损害其DNA结合活性。它不仅通过重新激活p53发挥抗肿瘤功能,还通过其他细胞机制发挥作用,例如将细胞ROS升高至毒性水平并激活UPR。
In vitro DMSO 46 mg/mL (194.39 mM)
Water 46 mg/mL (194.39 mM)
Ethanol 23 mg/mL (97.19 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 42.26 mL 211.3 mL 422.6 mL
0.5 mM 8.45 mL 42.26 mL 84.52 mL
1 mM 4.23 mL 21.13 mL 42.26 mL
5 mM 0.85 mL 4.23 mL 8.45 mL

*The above data is based on the productmolecular weight 236.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16833
作用机制 Activator (激活剂)
M. Wt 236.63
Formula C6H5ClN2O4S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 38275-34-2
Synonyms PK 11007, PK-11007
SMILES CS(=O)(=O)C1=NC=C(C(=N1)C(=O)O)Cl

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 PK11007 | PK11007 供应商 | 订购 PK11007 | PK11007 价格 | PK11007 生产商 | 订单 PK11007 | PK11007 代理商 | 购买 38275-34-2| 38275-34-2 供应商 | 订购 38275-34-2 | 38275-34-2 价格 | 38275-34-2 生产商 | 订单 38275-34-2 | 38275-34-2 代理商|buy PK11007 | PK11007 Supplier | purchase PK11007 | PK11007 cost | PK11007 manufacturer | order PK11007 | PK11007 distributor | buy 38275-34-2| 38275-34-2 Supplier | purchase 38275-34-2 | 38275-34-2 cost | 38275-34-2 manufacturer | order 38275-34-2 | 38275-34-2 distributor
Rewards