PKC 412 (Midostaurin)

Name: PKC 412 (Midostaurin)
SKU: A12650
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A12650

PKC 抑制剂

PKC 412 是一种广谱蛋白激酶抑制剂。它能抑制常规的 PKC 同型体 α/β/γ，PDFRβ，VEGFR2，Syk，Flk-1，Flt3，Cdk1/B，PKA，c-Kit，c-Fgr，c-Src，VEGFR1 和 EGFR。展示出强大的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
5mg	¥525.00	现货
10mg	¥840.00	现货
25mg	¥1,540.00	现货
50mg	¥2,380.00	现货
100mg	¥3,535.00	现货
500mg	¥8,015.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

PKC 412 is a broad spectrum protein kinase inhibitor. Inhibits conventional PKC isoforms α/β/γ, PDFRβ, VEGFR2, Syk, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. Displays potent antitumor activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12650
分子式	C35H30N4O4
分子量	570.64
CAS号	120685-11-2
SMILES	C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
其他名称	CGP 41251, PKC412, PKC-412, CGP41251, CGP-41251
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	90 mg/mL (157.72 mM)
	Water	Insoluble
	Ethanol	Warmed: 18 mg/mL
In vivo	5% DMSO+45% PEG 300+ddH2O	3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.52 mL	87.62 mL	175.24 mL
0.5 mM	3.5 mL	17.52 mL	35.05 mL
1 mM	1.75 mL	8.76 mL	17.52 mL
5 mM	0.35 mL	1.75 mL	3.5 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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