PKC-theta inhibitor
目录号: A19712
PKC-θ inhibitor
PKC-theta 抑制剂是一种选择性的 PKC-θ 抑制剂,其 IC50 为 12 nM。
Discription | PKC-theta inhibitor is a selective PKC-θinhibitor, with an IC50 of 12 nM. | ||
---|---|---|---|
Targets |
|
目录号 | A19712 |
---|---|
分子式 | C20H25F3N6O3 |
分子量 | 454.45 |
CAS号 | 736048-65-0 |
SMILES | FC(F)(F)OC1=CC=CC=C1CNC2=NC=C([N+]([O-])=O)C(NCC3CCC(CN)CC3)=N2 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 85 mg/mL (187.04 mM) | |
Water | Insoluble | ||
Ethanol | 28 mg/mL (61.61 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22 mL | 110.02 mL | 220.05 mL |
0.5 mM | 4.4 mL | 22 mL | 44.01 mL |
1 mM | 2.2 mL | 11 mL | 22 mL |
5 mM | 0.44 mL | 2.2 mL | 4.4 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2