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Protein Kinase C (PKC)

Protein Kinase C (PKC)

Inhibitory Selectivity

Catalog No.	Inhibitor Name	PKC	PKCα	PKCβ	PKCγ	PKCδ	PKCε	PKCζ	PKCη	PKCθ	PKCμ	Other
A10356	Enzastaurin		**	***	*		*
A11554	Sotrastaurin		****	****		****	****		****	****
A10864	Staurosporine		****		****	**	*	*	****			c-Fgr,phosphorylase kinase,S6 kinase
A13790	Go 6983		***	***	***	***		**			*
A13197	Bisindolylmaleimide I		**	***	**							PDGFR
A13514	Ro 31-8220 Mesylate		****	***	**		**
A12650	Midostaurin		**	**	**	*	*	*	*			PPK,KDR,c-Syk
A12419	Go6976	***	****	***								FLT3,JAK2
A10766	Quercetin											Sirtuin,Src,PI3Kγ
A10616	Myricitrin
A10196	Chelerythrine chloride	*
A10261	Bryostatin 1	***
A10286	Daphnetin	*										EGFR, PKA
A12399	Ruboxistaurin (LY333531)		*	****	*	*			**
A14871	PKC (19-36)	*

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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Go 6976

Catalog No. A12419
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PKC 抑制剂

Go6976是一种有效的PKC抑制剂，对PKC（大鼠脑），PKCα和PKCβ1的IC50分别为7.9 nM，2.3 nM和6.2 nM。也是JAK2和Flt3的有效抑制剂。了解更多

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