PKR-IN-C16

Name: PKR-IN-C16
SKU: A13538
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A13538

PKR Inhibitor

PKR 抑制剂是一种 草酰吲哚/咪唑衍生物，它结合到 PKR 的 ATP结合位点 并以 IC50 值为 186-210 nM 阻断自磷酸化。PKR 抑制剂可以保护人类神经母细胞瘤细胞免受由 鞘氨醇介导的内质网应激 触发的细胞损伤。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥525.00	现货
10mg	¥875.00	现货
25mg	¥1,820.00	现货
50mg	¥3,010.00	现货
100mg	¥4,655.00	现货
*10mM 1mL in DMSO**	¥735.00	现货
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Data Sheet

SDS

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生物活性

Discription	PKR Inhibitor is an oxindole/imidazole derivative that binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM.3 PKR Inhibitor protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.

产品信息

目录号	A13538
分子式	C13H8N4OS
分子量	268.3
CAS号	608512-97-6
SMILES	C1=CC2=C(C\3=C1NC(=O)/C3=C\C4=CN=CN4)SC=N2
其他名称	C16, GW 506033X
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	13 mg/mL (48.45 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	37.27 mL	186.36 mL	372.72 mL
0.5 mM	7.45 mL	37.27 mL	74.54 mL
1 mM	3.73 mL	18.64 mL	37.27 mL
5 mM	0.75 mL	3.73 mL	7.45 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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