PNU-282987 free base

Name: PNU-282987 free base
SKU: A22518
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A22518

nAChR 激动剂

PNU 282987 是一种高度选择性的 α7 nAChR 激动剂（Ki = 26 nM），对 α1β1γδ 和 α3β4 nAChRs 几乎没有阻断作用（IC50 ≥ 60 μM）。在 1 μM 浓度下，对一个包含 32 种受体的面板显示无活性，除了 5-HT3 受体（Ki = 930 nM）。

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规格	价格	库存
1mg	¥140.00	现货
5mg	¥175.00	现货
10mg	¥280.00	现货
25mg	¥630.00	现货
50mg	¥1,155.00	现货
100mg	¥2,205.00	现货
500mg	¥8,400.00	现货
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Data Sheet

SDS

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生物活性

Discription

PNU 282987 is a highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM).

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A22518
分子式	C14H17ClN2O
分子量	264.75
CAS号	711085-63-1
SMILES	O=C(N[C@H]1CN2CCC1CC2)C3=CC=C(Cl)C=C3
其他名称	PNU-282987, PNU 282987, PNU282987.
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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