Ponesimod

Name: Ponesimod
SKU: A13307

目录号: A13307

S1P1 receptor modulator

Ponesimod Chemical Structure

CAS NO. 854107-55-4

Ponesimod是一种口服活性，选择性鞘氨醇-1-磷酸受体1（S1P1）免疫调节剂，EC50为5.7 nM。

库存：现货

规格	价格	数量
5 mg	￥ 700.00
10 mg	￥ 1,190.00
25 mg	￥ 2,520.00

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生物活性

Ponesimod是一种口服活性，选择性鞘氨醇-1-磷酸受体1（S1P1）免疫调节剂，EC50为5.7 nM。

靶点信息

S1P1 receptor
5.7 nM(EC50)

溶解度 *

In vitro	DMSO	82 mg/mL (177.88 mM)
	Water	Insoluble
	Ethanol	82 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.69 mL	108.47 mL	216.93 mL
0.5 mM	4.34 mL	21.69 mL	43.39 mL
1 mM	2.17 mL	10.85 mL	21.69 mL
5 mM	0.43 mL	2.17 mL	4.34 mL

*The above data is based on the productmolecular weight 460.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13307
作用机制	Modulator (调节剂)
M. Wt	460.97
Formula	C23H25ClN2O4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	854107-55-4
Synonyms	ACT-128800
SMILES	O=C1N(C2=CC=CC=C2C)/C(S/C1=C\C3=CC=C(OC[C@H](O)CO)C(Cl)=C3)=N/CCC