Pozanicline

Name: Pozanicline
SKU: A21318
Price: 1400 CNY
Rating: 5 (288 reviews)

目录号: A21318

nAChR 激动剂

Pozanicline (ABT-089) 选择性激活神经元烟碱型乙酰胆碱受体（nAChR）亚型，是一种新型胆碱能药物，是 α4β2 nAChRs 的部分激动剂（Ki=16 nM），并且对 α6β2 和 α4β5β2 nAChR 亚型显示出高选择性，Pozanicline 对 [3H] cytisine 结合位点的结合亲和力（Ki, rat）为 16.7 nM。

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Grouped product items
规格	价格	库存
1mg	¥1,400.00	现货
5mg	¥3,500.00	现货
10mg	¥5,600.00	现货
25mg	¥10,605.00	现货
50mg	¥13,825.00	现货
100mg	¥17,465.00	现货
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Data Sheet

SDS

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Discription

Pozanicline (ABT-089) selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at α4β2 nAChRs (Ki=16 nM) and shows high selectivity for α6β2 and α4α5β2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A21318
分子式	C11H16N2O
分子量	192.26
CAS号	161417-03-4
SMILES	CC1=C(OC[C@H]2NCCC2)C=CC=N1
其他名称	ABT-089
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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