PP1

Name: PP1
SKU: A12724
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A12724

Src 抑制剂

PP1 是一种强效的 Src-家族酪氨酸激酶 抑制剂。它能抑制 p56lck 和 p59fynT（IC50 值分别为 5 和 6 nM）。相较于 ZAP-70 和 JAK2，显示出超过 8000 倍的选择性。PP1 还能适度抑制 p38、CSK、PDGF 受体、RET 衍生的癌蛋白、c-Kit 和 Bcr-Abl。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥525.00	现货
10mg	¥665.00	现货
25mg	¥1,435.00	现货
50mg	¥2,030.00	现货
100mg	¥3,220.00	现货
500mg	¥7,315.00	现货
*10mM 1mL in DMSO**	¥560.00	现货
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Data Sheet

SDS

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生物活性

Discription

PP1 is a potent inhibitor of Src-family tyrosine kinases. Inhibits p56lck and p59fynT (IC50 values are 5 and 6 nM respectively). Displays > 8000-fold selectivity over ZAP-70 and JAK2. Also moderately inhibits p38, CSK, PDGF receptors, RET-derived oncoproteins, c-Kit and Bcr-Abl

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12724
分子式	C16H19N5
分子量	281.36
CAS号	172889-26-8
SMILES	CC1=CC=C(C=C1)C2=NN(C3=C2C(=NC=N3)N)C(C)(C)C
其他名称	PP-1, PP 1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	4 mg/mL (14.21 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	35.54 mL	177.71 mL	355.42 mL
0.5 mM	7.11 mL	35.54 mL	71.08 mL
1 mM	3.55 mL	17.77 mL	35.54 mL
5 mM	0.71 mL	3.55 mL	7.11 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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