PP242 (Torkinib)

Name: PP242 (Torkinib)
SKU: A10746
Price: 175 CNY
Rating: 5 (3 reviews)

目录号: A10746

mTOR 抑制剂

3 篇发表文献

PP242 是一种强效且选择性的 mTOR 抑制剂，能够抑制 mTORC1 和 mTORC2。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥420.00	现货
25mg	¥630.00	现货
50mg	¥910.00	现货
100mg	¥1,610.00	现货
200mg	¥2,450.00	现货
500mg	¥4,060.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用PP242 (Torkinib)发表的3篇文献

Nobuyuki Kondo, .et al. , JCI Insight, 2023, Dec 22;8(24):e173688 PMID: 37917191

Hiroshi Fukamachi, .et al. , J Exp Clin Cancer Res, 2019, 38:127 PMID: 30866995

Fuse MJ, .et al. , Mol Cancer Ther, 2017, Oct;16(10):2130-2143 PMID: 28751539

生物活性

Discription

PP242 is a potent and selective mTOR inhibitor in both mTORC1 and mTORC2.

Targets

Target	Value

产品信息

目录号	A10746
分子式	C16H16N6O
分子量	308.3
CAS号	1092351-67-1
SMILES	CC(C)N1C2=C(/C(=C\3/C=C4C=C(C=CC4=N3)O)/N1)C(=NC=N2)N
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	57 mg/mL (184.86 mM)
	Water	Insoluble
	Ethanol	17 mg/mL (55.13 mM)
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.44 mL	162.18 mL	324.36 mL
0.5 mM	6.49 mL	32.44 mL	64.87 mL
1 mM	3.24 mL	16.22 mL	32.44 mL
5 mM	0.65 mL	3.24 mL	6.49 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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