PQR309 (Bimiralisib)

Name: PQR309 (Bimiralisib)
SKU: A15992
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A15992

PI3K inhibitor

PQR309 是一种口服生物利用度的广谱抑制剂，能够抑制磷脂酰肌醇-3-激酶（PI3K）和哺乳动物雷帕霉素靶蛋白（mTOR），具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥315.00	现货
5mg	¥455.00	现货
10mg	¥770.00	现货
25mg	¥1,575.00	现货
50mg	¥2,590.00	现货
100mg	¥3,990.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

PQR309 is an orally bioavailable pan inhibitor of phosphoinositide-3-kinases (PI3K) and inhibitor of the mammalian target of rapamycin (mTOR), with potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15992
分子式	C17H20F3N7O
分子量	411.39
CAS号	1225037-39-7
SMILES	NC1=NC=C(C2=NC(N3CCOCC3)=NC(N4CCOCC4)=N2)C(C(F)(F)F)=C1
其他名称	PQR-309, PQR 309
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	6 mg/mL (14.58 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.31 mL	121.54 mL	243.08 mL
0.5 mM	4.86 mL	24.31 mL	48.62 mL
1 mM	2.43 mL	12.15 mL	24.31 mL
5 mM	0.49 mL	2.43 mL	4.86 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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