PR-171 (Carfilzomib)

Name: PR-171 (Carfilzomib)
SKU: A11278
Price: 280 CNY
Rating: 5 (6 reviews)

目录号: A11278

Proteasome 抑制剂

6 篇发表文献

PR-171（卡非佐米）是一种四肽环氧酮，并且是一种选择性蛋白酶体抑制剂。它是环氧霉素的类似物。

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Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥420.00	现货
25mg	¥630.00	现货
50mg	¥910.00	现货
100mg	¥1,260.00	现货
200mg	¥2,170.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用PR-171 (Carfilzomib)发表的6篇文献

Andrew Thorne, .et al. , PLoS One, 2023, Jun 8;18(6):e0286783 PMID: 37289679

Mahmood Barani, .et al. , J Drug Deliv Sci Technol, 2023, 81: 104268

Ori Kalid, .et al. , Chem Biol Drug Des, 2022, Mar 24 PMID: 35322538

Abbas Rahdar, .et al. , Journal of Molecular Liquids, 2022, 346: 118271

Sadegh Zarei, .et al. , J Appl Biotechnol Rep, 2019, June;6(2):45-49

Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358

生物活性

Discription

PR-171 (Carfilzomib) is a tetrapeptide epoxyketone and a selective proteasome inhibitor. It is an analog of epoxomicin.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11278
分子式	C40H57N5O7
分子量	719.9
CAS号	868540-17-4
SMILES	CC(C)C[C@@H](C(=O)[C@]1(CO1)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
其他名称	PR-171-007
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	46 mg/mL (63.89 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+2%Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	13.89 mL	69.45 mL	138.91 mL
0.5 mM	2.78 mL	13.89 mL	27.78 mL
1 mM	1.39 mL	6.95 mL	13.89 mL
5 mM	0.28 mL	1.39 mL	2.78 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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