Praliciguat
目录号: A19315
guanylate cyclase stimulator
Praliciguat (IW-1973) 是一种强效且可口服的可溶性鸟苷酸环化酶刺激剂,增强NO信号传导,作为一种血管扩张剂。Praliciguat (IW-1973) 在HEK-293细胞中刺激sGC,其EC50为197 nM。
Discription | Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM. |
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目录号 | A19315 |
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分子式 | C21H14F8N6O2 |
分子量 | 534.36 |
CAS号 | 1628730-49-3 |
SMILES | FC1=C(C=CC=C1)CN2C(C3=NOC=C3)=CC(C4=NC=C(F)C(NCC(C(F)(F)F)(O)C(F)(F)F)=N4)=N2 |
其他名称 | IW-1973, IW1973, IW 1973 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2