Rilzabrutinib (PRN1008)
目录号: A19999
BTK inhibitor
PRN1008 是一种可逆的共价、选择性和口服活性的 Bruton's Tyrosine Kinase (BTK) 抑制剂,其 IC50 为 1.3 nM。
Discription | PRN1008 is a reversible covalent, selective and oral active inhibitor of Bruton??s Tyrosine Kinase (BTK), with an IC50 of 1.3 nM. | |||||
---|---|---|---|---|---|---|
Targets |
|
|||||
Cell Research |
|
目录号 | A19999 |
---|---|
分子式 | C36H40FN9O3 |
分子量 | 665.76 |
CAS号 | 1575596-29-0 |
SMILES | NC1=C2C(C3=C(C=C(OC4=CC=CC=C4)C=C3)F)=NN([C@H]5CN(CCC5)C(/C(C#N)=C/C(C)(N6CCN(C7COC7)CC6)C)=O)C2=NC=N1 |
其他名称 | PRN 1008, PRN-1008 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2