ProMatrilysin

Catalog No.: AP4230

产品概述

ProMatrix Metalloproteinase-7 Recombinant

Product Details

Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3.4.24.23) cleaves a number of substrates including collagen types IV and X, elastin, fibronectin, gelatin, laminin and proteoglycans. MMP-7 is closely related to the stromelysin family members but is encoded by a different gene. MMP-7 is the smallest of all the MMPs consisting of a pro-peptide domain and a catalytic domain. It lacks the hemopexin-like domain common to other members of the MMPs. MMP-7 is secreted as a 28 kDa proenzyme and can be activated in vitro by organomercurials and trypsin and in vivo by MMP-3 to a 18 kDa active MMP-7 enzyme. Once activated, MMP-7 can activate pro-MMP-1 and pro-MMP-9 but not pro-MMP-2. MMP-7 is widely expressed having been reported in elevated levels in cycling endometrium as well as in colorectal cancers and adenomas, hepatocellular carcinomas, rectal carcinomas, and approximately 50% of gliomas.

库存: 现货

规格 价格 数量
ProMatrilysin 5µg
¥ 770.00
ProMatrilysin 20µg
¥ 2,030.00
ProMatrilysin 1mg
¥ 80,080.00

详情

ProMatrix Metalloproteinase-7 Recombinant
目录号 AP4230
Physical Appearance Sterile clear liquid solution.
Formulation The protein contains the following additives 25mM Tris-HCl (pH 7.5),150mM NaCl, 5mM CaCl2, 0.01% Brij-35 and 0.02% NaN3.
Protein biological activity The specific activity was found to be 1400 IU/mg.
Uniprot ACC# 0
Purity Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Source Escherichia Coli.
Transportation method Shipped with Ice Packs

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