Prostanoid Receptors
-
Treprostinil sodium
Catalog No. A21046 DP1/EP2 agonistTreprostinil sodium is a potent DP1 and EP2 agonist with EC50 values of 0.6??0.1 and 6.2??1.2 nM, respectively. 了解更多 -
CJ-42794
Catalog No. A21948 EP4 antagonistCJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist, inhibits [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5, a binding affinity that was at least 200-fold more selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3). 了解更多 -
AGN 210676
Catalog No. A21281 prostaglandin EP2 agonistAGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM. 了解更多 -
Terutroban
Catalog No. A20884 thromboxane-prostaglandin receptor antagonistTerutroban is a thromboxane-prostaglandin receptor antagonist. 了解更多 -
MK-2894 sodium salt
Catalog No. A11498 EP4 antagonistMK-2894 sodium salt is a highly potent and selective second generation EP4 antagonist. 了解更多 -
(+)-Cloprostenol
Catalog No. A12979 prostaglandin F2α (PGF2α) analogue(+)-Cloprostenol is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor. 了解更多 -
ONO-AE3-208
Catalog No. A11516 EP4 antagonistONO-AE3-208 is an EP4 antagonist, and suppresses cell invasion, migration, and metastasis of prostate cancer. 了解更多 -
CAY10471 Racemate
Catalog No. A11760 Prostaglandin D2 receptor CRTH2 antagonistCAY10471 Racemate (TM30089 Racemate) is a potent and highly selective prostaglandin D2 receptor CRTH2 antagonist. 了解更多 -
GSK726701A
Catalog No. A20101 EP4 partial agonistGSK726701A is a novel prostaglandin E2 receptor 4 (EP4) partial agonist with a pEC50 of 7.4. 了解更多 -
Dinoprost tromethamine
Catalog No. A17505 Prostaglandin Receptor inhibitorDinoprost Tromethamine, also known as Dinoprost Trometamol, is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. 了解更多 -
Benorylate
Catalog No. A17501 Prostaglandin Receptor inhibitorBenorilate, also known as Win-11450, is an ester of aspirin and paracetamol with analgesic, antipyretic, and anti-inflammatory activity used in the treatment of rheumatoid diseases. Benorilate has less severe side effects than aspirin. 了解更多 -
Tafluprost
Catalog No. A17442 prostaglandin analogueTafluprost, also known as MK2452 and AFP-168, is a prostaglandin analogue used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. 了解更多 -
GSK-269984A
Catalog No. A17096 -
Grapiprant (CJ-023423)
Catalog No. A15964 prostaglandin EP4 receptor 拮抗剂Grapiprant (CJ-023423)是一种具有抗痛觉过敏特性的新型,有效且选择性的前列腺素EP4受体拮抗剂。 了解更多 -
TG6-10-1
Catalog No. A15968 -
CP544326 (Taprenepag)
Catalog No. A15853 -
PF-04418948
Catalog No. A12894 -
MF498
Catalog No. A15532 -
NS-304 (Selexipag)
Catalog No. A13880 prostacyclin receptor 激动剂NS-304 (Selexipag)是一种选择性的前列环素IP1受体激动剂(人和大鼠IP受体的Ki值为260和2100 nM,EP1-4,DP,FP和TP受体的Ki值为> 10μM)。 了解更多 -
BAY-u 3405
Catalog No. A13751 -
Cloprostenol (sodium salt)
Catalog No. A13498 cloprostenol是前列腺素F2α(PGF2α)的合成类似物。它在仓鼠和大鼠中终止妊娠的效力分别是PGF2α的200倍和100倍,而没有与PGF2α相关的副作用。 了解更多 -
Ozagrel hydrochloride
Catalog No. A11742 Thromboxane A2 synthesis 抑制剂Ozagrel hydrochloride是一种抗血小板剂,用作血栓烷a2合成抑制剂。 了解更多 -
Laropiprant (MK0524)
Catalog No. A11483 DP1 抑制剂Laropiprant (MK0524)与烟酸合用可降低血液胆固醇。是一种有效的,选择性的 DP receptor 拮抗剂,Ki 值为 0.57 nM,对 TP 受体的 Ki 值为 2.95 nM。 了解更多