PROTAC BET degrader-2
目录号: A18785
PROTAC BET degrader
PROTAC BET degrader-2 是一种高效的溴结构域和额外末端(BET)蛋白降解剂,其在 RS4;11 细胞中抑制细胞生长的 IC50 值为 9.6 nM,并能够实现肿瘤退化。
Discription | PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression. | |||||
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Cell Research |
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目录号 | A18785 |
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分子式 | C41H42N10O6 |
分子量 | 770.84 |
CAS号 | 2093388-33-9 |
SMILES | O=C(C1=NC(NC2=CC(C3CC3)=NN2CC)=C4C(NC5=C4C=C(OC)C(C6=C(C)ON=C6C)=C5)=N1)NCCCC7=CC=CC8=C7CN(C(CC9)C(NC9=O)=O)C8=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2