目录号
产品名
应用
产品描述
文献引用
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NAE Inhibitor
NAE 抑制剂 MLN4924 与 NAE 结合并抑制 NAE，这可能导致抑制肿瘤细胞的增殖和存活。- Takumi Ito, .et al. , Research Square, 2023, 2023
- Blue-leaf A. Cordes, .et al. , Cancers (Basel), 2023, Mar; 15(6): 1846 PMID: 36980731
- Min Dong, .et al. , J Immunother Cancer, 2022, Oct;10(10):e005270 PMID: 36198437
- Corentin Mallet, .et al. , J Virol, 2021, Dec 22;JVI0142721 PMID: 34936483
- Nobuyuki Shimizu, .et al. , Commun Biol, 2021, Nov 11;4(1):1277 PMID: 34764413
- Jalila Chagraoui, .et al. , Cell Stem Cell, 2021, Jan 7;28(1):48-62.e6 PMID: 33417871
- Stephan Riesenberg, .et al. , Nat Commun, 2018, 9: 2164 PMID: 29867139
- Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
- Richard J. Kraus, .et al. , PLoS Pathog, 2017, Jun; 13(6): e1006404 PMID: 28617871
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NAE inhibitor
TAS4464（盐酸盐）是一种高效且选择性的 NEDD8 激活酶 (NAE) 抑制剂，其 IC50 为 0.955 nM。
