PROTACs
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FKBP12 PROTAC dTAG-7
Catalog No. A19081 heterobifunctional degraderFKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional degrader. 了解更多 -
PROTAC BET degrader-2
Catalog No. A18785 PROTAC BET degraderPROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression. 了解更多 -
dBET1
Catalog No. A16858 -
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MZ1
Catalog No. A17014 -
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VH032-cyclopropane-F
Catalog No. A18417 VH032-based VHL ligandVH032-cyclopropane-F is the VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein (e.g., SMARCA BD ligand) by a linker to form PROTACs (e.g., PROTAC 1). 了解更多 -
Thalidomide fluoride
Catalog No. A12144 Thalidomide-based Cereblon ligandThalidomide fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966). 了解更多 -
E3 ligase Ligand 14
Catalog No. A19028 E3 ubiquitin ligase ligandE3 ligase Ligand 14 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 14 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins. 了解更多 -
E3 ligase Ligand 10
Catalog No. A19045 E3 ubiquitin ligase ligandE3 ligase Ligand 10 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 10 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins. 了解更多 -
E3 ligase Ligand 9
Catalog No. A19051 E3 ubiquitin ligase ligandE3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 9 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. 了解更多 -
Thalidomide-O-amido-C3-NH2 (TFA)
Catalog No. A21801 E3 ligase ligand-linker conjugateThalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多 -
cIAP1 Ligand-Linker Conjugates 15 hydrochloride
Catalog No. A21758 E3 ligase ligand-linker conjugatecIAP1 Ligand-Linker Conjugates 15 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 hydrochloride can be used to design SNIPERs. 了解更多 -
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride
Catalog No. A21753 E3 ligase ligand-linker conjugatecIAP1 Ligand-Linker Conjugates 11 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 Hydrochloride can be used to design SNIPERs. 了解更多 -
Lenalidomide-C5-NH2
Catalog No. A18414 Lenalidomide-based Cereblon ligandLenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs. 了解更多 -
Pomalidomide-PEG4-Ph-NH2
Catalog No. A12066 E3 ligase ligand-linker conjugatePomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. 了解更多 -
CCK2R Ligand-Linker Conjugates 1
Catalog No. A18411 ligand-linker conjugateCCK2R Ligand-Linker Conjugates 1 is a ligand-linker conjugate, which conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) via a hydrophilic peptide linker. 了解更多 -
Thalidomide-O-amido-PEG2-C2-NH2 (TFA)
Catalog No. A21634 E3 ligase ligand-linker conjugateThalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology. 了解更多 -
Thalidomide-O-amido-C6-NH2 (TFA)
Catalog No. A21639 E3 ligase ligand-linker conjugateThalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多 -
(S,R,S)-AHPC-PEG3-NH2
Catalog No. A21660 E3 ligase ligand-linker conjugate(S,R,S)-AHPC-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. 了解更多 -
(S,R,S)-AHPC-PEG2-NH2
Catalog No. A21665 E3 ligase ligand-linker conjugate(S,R,S)-AHPC-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in PROTAC technology. 了解更多 -
(S,R,S)-AHPC-PEG4-NH2
Catalog No. A21671 E3 ligase ligand-linker conjugate(S,R,S)-AHPC-PEG4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. 了解更多 -
Pomalidomide-C2-NH2
Catalog No. A18855 E3 ligase ligand-linker conjugatePomalidomide-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a PEG linker used in PROTAC technology. 了解更多 -
Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH
Catalog No. A18842 E3 ligase ligand-linker conjugatePomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多 -
Pomalidomide-C2-NH2 hydrochloride
Catalog No. A21768 E3 ligase ligand-linker conjugatePomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology. 了解更多 -
(S,R,S)-AHPC-C3-NH2
Catalog No. A18818 E3 ligase ligand-linker conjugate(S,R,S)-AHPC-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology. 了解更多