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PRT 062070 (Cerdulatinib)是一种新型的口服双脾酪氨酸激酶(Syk)和janus激酶(JAK)抑制剂。Cerdulatinib优先抑制各种细胞类型中JAK1和JAK3依赖性细胞因子介导的信号传导和功能性反应。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.44 mL | 112.22 mL | 224.45 mL |
0.5 mM | 4.49 mL | 22.44 mL | 44.89 mL |
1 mM | 2.24 mL | 11.22 mL | 22.44 mL |
5 mM | 0.45 mL | 2.24 mL | 4.49 mL |
*The above data is based on the productmolecular weight 445.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A14147 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 445.54 |
Formula | C20H27N7O3S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1198300-79-6 |
Synonyms | Cerdulatinib,PRT2070,PRT-2070,PRT 2070,PRT-062070,PRT062070 |
SMILES | CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N |
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