PRX-08066

Name: PRX-08066
SKU: A13267

目录号: A13267

5-HT2B receptor 拮抗剂

PRX-08066 Chemical Structure

CAS NO. 866206-54-4

PRX-08066是一种新型的5-HT受体2B（5-HT2BR）拮抗剂，IC50为3.4 nM，，可减轻单芥子碱诱导的大鼠肺动脉高压和右室肥大。

库存：现货

规格	价格	数量
5 mg	￥ 1,330.00
10 mg	￥ 1,960.00
25 mg	￥ 3,990.00

大包装询价

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

PRX-08066是一种新型的5-HT受体2B（5-HT2BR）拮抗剂，IC50为3.4 nM，，可减轻单芥子碱诱导的大鼠肺动脉高压和右室肥大。

溶解度 *

In vitro	DMSO	92 mg/mL (177.61 mM)
	Water	92 mg/mL (177.61 mM)
	Ethanol	86 mg/mL (166.03 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.88 mL	124.41 mL	248.82 mL
0.5 mM	4.98 mL	24.88 mL	49.76 mL
1 mM	2.49 mL	12.44 mL	24.88 mL
5 mM	0.5 mL	2.49 mL	4.98 mL

*The above data is based on the productmolecular weight 401.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13267
作用机制	Antagonist (拮抗剂)
M. Wt	401.89
Formula	C19H17ClFN5S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	866206-54-4
Synonyms	PRX08066, PRX 08066
SMILES	C1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N