Sofosbuvir (PSI-7977)

Name: Sofosbuvir (PSI-7977)
SKU: A11529
Price: 280 CNY
Rating: 5 (1 reviews)

目录号: A11529

HCV Nucleotide Inhibitor

1 篇发表文献

PSI-7977 是 PSI-7851 的磷酰胺前药，PSI-7851 是一种核苷类似物，当其磷酸化后，能够抑制丙型肝炎病毒的RNA依赖性RNA聚合酶（EC50 = 92 nM）。

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Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥350.00	现货
25mg	¥420.00	现货
50mg	¥525.00	现货
100mg	¥630.00	现货
500mg	¥980.00	现货
1g	¥1,155.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Sofosbuvir (PSI-7977)发表的1篇文献

Miyayama Y, .et al. , Microbiol Immunol, 2019, Dec 19 PMID: 31854467

生物活性

Discription

PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11529
分子式	C22H29FN3O9P
分子量	529.45
CAS号	1190307-88-0
SMILES	C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3
其他名称	GI-7977
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 86 mg/mL (162.43 mM)
	Water	Warmed: 9 mg/mL (16.99 mM)
	Ethanol	86 mg/mL (162.43 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.89 mL	94.44 mL	188.88 mL
0.5 mM	3.78 mL	18.89 mL	37.78 mL
1 mM	1.89 mL	9.44 mL	18.89 mL
5 mM	0.38 mL	1.89 mL	3.78 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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