PT2399
目录号: A19787
HIF-2α antagonist
PT2399 是一种强效且选择性的 HIF-2α 拮抗剂，能直接与 HIF-2α PAS B 结构域结合，其 IC50 为 6 nM。PT2399 在体内显示出强大的抗肿瘤活性。
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生物活性
| Discription | PT2399 is a potent and selective HIF-2α antagonist, which directly binds to HIF-2α PAS B domain with an IC50 of 6 nM. PT2399 displays potent antitumor activity in vivo. |
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产品信息
| 目录号 | A19787 |
|---|---|
| 分子式 | C17H10F5NO4S |
| 分子量 | 419.32 |
| CAS号 | 1672662-14-4 |
| SMILES | N#CC1=CC(F)=CC(OC2=CC=C(S(=O)(C(F)F)=O)C3=C2CC(F)(F)[C@H]3O)=C1 |
| 其他名称 | PT 2399, PT-2399 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 81 mg/mL (193.17 mM) | |
| Water | Insoluble | ||
| Ethanol | 81 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.85 mL | 119.24 mL | 238.48 mL |
| 0.5 mM | 4.77 mL | 23.85 mL | 47.7 mL |
| 1 mM | 2.38 mL | 11.92 mL | 23.85 mL |
| 5 mM | 0.48 mL | 2.38 mL | 4.77 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 PT2399 | PT2399 供应商 | PT2399 花费 | PT2399 生产商 | 订购 PT2399 | PT2399 代理商
| 购买 1672662-14-4 | 1672662-14-4 供应商 | 1672662-14-4 花费 | 1672662-14-4 生产商 | 订购 1672662-14-4 | 1672662-14-4 代理商