PTC124 (Ataluren)

Name: PTC124 (Ataluren)
SKU: A10758
Price: 175 CNY
Rating: 5 (2 reviews)

目录号: A10758

CFTR 抑制剂

2 篇发表文献

PTC124，也被称为Ataluren，是CFTR-G542X nonsense allele抑制剂。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥245.00	现货
25mg	¥525.00	现货
50mg	¥805.00	现货
100mg	¥1,330.00	现货
200mg	¥1,610.00	现货
500mg	¥2,730.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用PTC124 (Ataluren)发表的2篇文献

L Kadunc, .et al. , FEBS Lett, 2020, May 13 PMID: 32401336

Caspi M, .et al. , J Mol Med (Berl), 2016, Apr;94(4):469-82 PMID: 26620677

生物活性

Discription

PTC124 also known as Ataluren is CFTR-G542X nonsense allele inhibitor.

Targets

Target	Value

产品信息

目录号	A10758
分子式	C15H9FN2O3
分子量	284.2
CAS号	775304-57-9
SMILES	C1=CC=C(C(=C1)C2=NC(=NO2)C3=CC(=CC=C3)C(=O)O)F
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	55 mg/mL (193.49 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	35.19 mL	175.93 mL	351.86 mL
0.5 mM	7.04 mL	35.19 mL	70.37 mL
1 mM	3.52 mL	17.59 mL	35.19 mL
5 mM	0.7 mL	3.52 mL	7.04 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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