PTC299

Name: PTC299
SKU: A18935
Price: 770 CNY
Rating: 5 (288 reviews)

目录号: A18935

VEGFA inhibitor

PTC299 是一种有效的、可口服的 VEGFA 抑制剂，其靶向 二氢乳酸脱氢酶 (DHODH)，导致白血病（包括急性髓细胞性白血病）中的细胞生长抑制和分化，将 DHODH 调控与应激诱导的 VEGFA 和 血管生成 相联系。

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Grouped product items
规格	价格	库存
1mg	¥770.00	现货
5mg	¥1,750.00	现货
10mg	¥2,660.00	现货
25mg	¥4,550.00	现货
50mg	¥6,475.00	现货
100mg	¥8,855.00	现货
*10mM 1mL in DMSO**	¥1,785.00	现货
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Data Sheet

SDS

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生物活性

Discription

PTC299 is a potent, orally bioavailable VEGFA inhibitor, targets dihydroorotate dehydrogenase (DHODH), resulting in cell growth inhibition and differentiation in leukemias, including acute myeloid leukemia, linking DHODH regulation and stress-induced VEGFA and angiogenesis.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A18935
分子式	C25H20Cl2N2O3
分子量	467.34
CAS号	1256565-36-2
SMILES	O=C(N([C@H]1C2=CC=C(OC)C=C2)CCC3=C1NC4=C3C=C(Cl)C=C4)OC5=CC=C(Cl)C=C5
其他名称	PTC-299, PTC 299
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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