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(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation .
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.07 mL | 135.37 mL | 270.74 mL |
0.5 mM | 5.41 mL | 27.07 mL | 54.15 mL |
1 mM | 2.71 mL | 13.54 mL | 27.07 mL |
5 mM | 0.54 mL | 2.71 mL | 5.41 mL |
*The above data is based on the productmolecular weight 369.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A21887 |
---|---|
作用机制 | Modulator (调节剂) |
M. Wt | 369.36 |
Formula | C20H17F2N3O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 851881-59-9 |
Synonyms | BX 471, BX-471 |
SMILES | O=C(N1C[C@H](C2=NC(C3=CC=C(C=C3)F)=NO2)CCC1)C4=CC=C(C=C4)F |
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