(R)-GNE-140

Name: (R)-GNE-140
SKU: A21863
Price: 420 CNY
Rating: 5 (288 reviews)

目录号: A21863

LDHA inhibitor

(R)-GNE-140 是一种强效的乳酸脱氢酶 A（LDHA）抑制剂，对 LDHA 和 LDHB 的 IC50 分别为 3 nM 和 5 nM；(R)-GNE-140 的效力是 S 对映体的 18 倍。

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Grouped product items
规格	价格	库存
1mg	¥420.00	现货
5mg	¥1,085.00	现货
10mg	¥1,540.00	现货
25mg	¥2,590.00	现货
50mg	¥3,535.00	现货
100mg	¥4,830.00	现货
*10mM 1mL in DMSO**	¥1,190.00	现货
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Data Sheet

SDS

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生物活性

Discription

(R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor, with IC50s of 3 nM and 5 nM for LDHA and LDHB, respectively; (R)-GNE-140 is 18-fold more potent than S enantiomer.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A21863
分子式	C25H23ClN2O3S2
分子量	499.04
CAS号	2003234-63-5
SMILES	O=C1N[C@@](C2=CSC=C2)(C3=CC=C(N4CCOCC4)C=C3)CC(O)=C1SC5=CC=CC=C5Cl
其他名称	GNE140, GNE 140
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	88 mg/mL (176.33 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.04 mL	100.19 mL	200.38 mL
0.5 mM	4.01 mL	20.04 mL	40.08 mL
1 mM	2 mL	10.02 mL	20.04 mL
5 mM	0.4 mL	2 mL	4.01 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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