R112
目录号: A14161
Syk 抑制剂
R112 是一种 Syk 抑制剂。R112 抑制了由抗IgE交联引起的肥大细胞脱颗粒，并且还阻断了 白三烯C4 的产生以及所有测试过的 促炎细胞因子。
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生物活性
| Discription | R112 is a Syk inhibitor. R112 inhibited degranulation induced by anti-IgE cross-linking in mast cells and also blocked leukotriene C4 production and all proinflammatory cytokines tested. |
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产品信息
| 目录号 | A14161 |
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| 分子式 | C16H13FN4O2 |
| 分子量 | 312.3 |
| CAS号 | 575474-82-7 |
| SMILES | C1=CC(=CC(=C1)O)NC2=NC(=NC=C2F)NC3=CC(=CC=C3)O |
| 其他名称 | R 112, R-112 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 61 mg/mL (195.32 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.02 mL | 160.1 mL | 320.2 mL |
| 0.5 mM | 6.4 mL | 32.02 mL | 64.04 mL |
| 1 mM | 3.2 mL | 16.01 mL | 32.02 mL |
| 5 mM | 0.64 mL | 3.2 mL | 6.4 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 R112 | R112 供应商 | R112 花费 | R112 生产商 | 订购 R112 | R112 代理商
| 购买 575474-82-7 | 575474-82-7 供应商 | 575474-82-7 花费 | 575474-82-7 生产商 | 订购 575474-82-7 | 575474-82-7 代理商